HUMAnN Functional Profiler Skill
Purpose
Provide HUMAnN functional profiling for metagenomic pathway analysis.
Capabilities
- Gene family quantification
- MetaCyc pathway abundance
- UniRef annotation
- Stratified functional profiles
- Pathway coverage analysis
- Custom database integration
Usage Guidelines
- Run taxonomic profiling first
- Quantify gene families and pathways
- Stratify by organism when relevant
- Analyze pathway coverage
- Compare functional profiles
- Document database versions
Dependencies
- HUMAnN3
- eggNOG-mapper
- Prokka
Process Integration
- Shotgun Metagenomics Pipeline (shotgun-metagenomics)