Agent-Skills.md

Agent Skills: Bio-Research Start

Set up your bio-research environment and explore available tools. Use when first getting oriented with the plugin, checking which literature, drug-discovery, or visualization MCP servers are connected, or surveying available analysis skills before starting a new project.

UncategorizedID: anthropics/knowledge-work-plugins/start

Repository

anthropics/knowledge-work-plugins
anthropicsLicense: Apache-2.0
22,4892,645

Install this agent skill to your local

pnpm dlx add-skill https://github.com/anthropics/knowledge-work-plugins/tree/HEAD/bio-research/skills/start

Skill Files

Browse the full folder contents for start.

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bio-research/skills/start/SKILL.md

Skill Metadata

Name
start
Description
Set up your bio-research environment and explore available tools. Use when first getting oriented with the plugin, checking which literature, drug-discovery, or visualization MCP servers are connected, or surveying available analysis skills before starting a new project.

Bio-Research Start

If you see unfamiliar placeholders or need to check which tools are connected, see CONNECTORS.md.

You are helping a biological researcher get oriented with the bio-research plugin. Walk through the following steps in order.

Step 1: Welcome

Display this welcome message:

Bio-Research Plugin

Your AI-powered research assistant for the life sciences. This plugin brings
together literature search, data analysis pipelines,
and scientific strategy — all in one place.

Step 2: Check Available MCP Servers

Test which MCP servers are connected by listing available tools. Group the results:

Literature & Data Sources:

  • ~~literature database — biomedical literature search
  • ~~literature database — preprint access (biology and medicine)
  • ~~journal access — academic publications
  • ~~data repository — collaborative research data (Sage Bionetworks)

Drug Discovery & Clinical:

  • ~~chemical database — bioactive compound database
  • ~~drug target database — drug target discovery platform
  • ClinicalTrials.gov — clinical trial registry
  • ~~clinical data platform — clinical trial site ranking and platform help

Visualization & AI:

  • ~~scientific illustration — create scientific figures and diagrams
  • ~~AI research platform — AI for biology (histopathology, drug discovery)

Report which servers are connected and which are not yet set up.

Step 3: Survey Available Skills

List the analysis skills available in this plugin:

| Skill | What It Does | |-------|-------------| | Single-Cell RNA QC | Quality control for scRNA-seq data with MAD-based filtering | | scvi-tools | Deep learning for single-cell omics (scVI, scANVI, totalVI, PeakVI, etc.) | | Nextflow Pipelines | Run nf-core pipelines (RNA-seq, WGS/WES, ATAC-seq) | | Instrument Data Converter | Convert lab instrument output to Allotrope ASM format | | Scientific Problem Selection | Systematic framework for choosing research problems |

Step 4: Optional Setup — Binary MCP Servers

Mention that two additional MCP servers are available as separate installations:

  • ~~genomics platform — Access cloud analysis data and workflows Install: Download txg-node.mcpb from https://github.com/10XGenomics/txg-mcp/releases
  • ~~tool database (Harvard MIMS) — AI tools for scientific discovery Install: Download tooluniverse.mcpb from https://github.com/mims-harvard/ToolUniverse/releases

These require downloading binary files and are optional.

Step 5: Ask How to Help

Ask the researcher what they're working on today. Suggest starting points based on common workflows:

  1. Literature review — "Search ~~literature database for recent papers on [topic]"
  2. Analyze sequencing data — "Run QC on my single-cell data" or "Set up an RNA-seq pipeline"
  3. Drug discovery — "Search ~~chemical database for compounds targeting [protein]" or "Find drug targets for [disease]"
  4. Data standardization — "Convert my instrument data to Allotrope format"
  5. Research strategy — "Help me evaluate a new project idea"

Wait for the user's response and guide them to the appropriate tools and skills.