Agent Skills: Clinical Reports

Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries). Full support with templates, regulatory compliance (HIPAA, FDA, ICH-GCP), and validation tools.

UncategorizedID: drshailesh88/integrated_content_OS/clinical-reports

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skills/cardiology/clinical-reports/SKILL.md

Clinical Reports

Professional clinical documentation covering case reports, diagnostic reports, trial reports, and patient documentation.

Triggers

  • User needs to write a case report
  • User is documenting clinical findings
  • User wants to format trial results
  • User needs diagnostic report structure
  • User is preparing clinical documentation

Report Types

1. Case Reports (CARE Guidelines)

Required Sections: | Section | Content | |---------|---------| | Title | Diagnosis and intervention focus | | Abstract | Structured: background, case, conclusion | | Introduction | Why this case matters | | Patient Information | Demographics, history (de-identified) | | Clinical Findings | Presentation, exam, initial assessment | | Timeline | Chronological events | | Diagnostic Assessment | Workup, reasoning, differentials | | Therapeutic Intervention | Treatment details | | Follow-up and Outcomes | Results, adherence, adverse events | | Discussion | Context, rationale, limitations |

HIPAA De-identification (Remove 18 identifiers):

  • Names, geographic data, dates (except year)
  • Phone, fax, email, SSN, MRN
  • Health plan numbers, account numbers
  • License/vehicle numbers, device IDs
  • URLs, IP addresses, biometrics, photos

2. Diagnostic Reports

Cardiology-Specific

Echocardiography Report Structure:

  • Patient demographics
  • Indication
  • Technical quality
  • LV size and function (EF method specified)
  • RV assessment
  • Valvular assessment (stenosis/regurgitation grading)
  • Other findings
  • Comparison with prior
  • Impression and recommendations

Cardiac Catheterization Report:

  • Procedure indication
  • Access and technique
  • Hemodynamics (pressures, gradients)
  • Coronary anatomy (dominance, lesions)
  • LV function
  • Intervention performed (if any)
  • Complications
  • Recommendations

Electrophysiology Report:

  • Indication
  • Baseline intervals
  • Findings (inducibility, mechanism)
  • Ablation details (if performed)
  • Outcomes and endpoints
  • Recommendations

3. Clinical Trial Reports

Serious Adverse Event (SAE) Reports

Timeline Requirements:

  • Fatal/life-threatening: 7 days
  • Other serious: 15 days

Required Elements:

  • Event description and onset date
  • Seriousness criteria met
  • Causality assessment
  • Action taken with study drug
  • Outcome
  • Relevant medical history
  • Concomitant medications

Clinical Study Report (ICH-E3 Structure)

  1. Title page
  2. Synopsis
  3. Table of contents
  4. List of abbreviations
  5. Ethics
  6. Investigators and study sites
  7. Introduction
  8. Study objectives
  9. Investigational plan
  10. Study patients
  11. Efficacy evaluation
  12. Safety evaluation
  13. Discussion and conclusions
  14. Tables, figures, graphs
  15. Reference list
  16. Appendices

4. Patient Documentation

SOAP Note Format

S (Subjective): Patient's reported symptoms, history
O (Objective): Vital signs, exam findings, test results
A (Assessment): Diagnosis, clinical reasoning
P (Plan): Treatment, follow-up, patient education

History & Physical Structure

  • Chief complaint
  • History of present illness
  • Past medical/surgical history
  • Medications and allergies
  • Family history
  • Social history
  • Review of systems
  • Physical examination
  • Assessment and plan

Discharge Summary Elements

  • Admission diagnosis
  • Hospital course
  • Procedures performed
  • Discharge diagnosis
  • Discharge medications (with changes noted)
  • Follow-up appointments
  • Patient education provided
  • Contingency instructions

Compliance Requirements

Regulatory Standards

| Regulation | Applies To | Key Requirements | |------------|------------|------------------| | HIPAA | All US healthcare | Privacy, minimum necessary | | 21 CFR Part 11 | Electronic records | Audit trails, signatures | | ICH-GCP | Clinical trials | Protocol adherence, consent | | FDA 21 CFR 312 | INDs | Safety reporting |

Standardized Terminology

  • SNOMED CT: Clinical terms
  • LOINC: Laboratory tests
  • ICD-10-CM: Diagnoses
  • CPT: Procedures
  • RxNorm: Medications

Prohibited Abbreviations (Joint Commission)

| Don't Use | Problem | Use Instead | |-----------|---------|-------------| | U | Mistaken for 0 | "unit" | | IU | Mistaken for IV | "international unit" | | QD, QOD | Confused | "daily," "every other day" | | Trailing zero (1.0) | Decimal missed | 1 mg | | No leading zero (.5) | Decimal missed | 0.5 mg | | MS, MSO4, MgSO4 | Confused | "morphine" or "magnesium" |

Quality Standards

Documentation Must Be

  • Complete: All relevant information included
  • Accurate: Facts verified, no assumptions
  • Timely: Documented promptly
  • Clear: Understandable to readers
  • Compliant: Meets regulatory requirements

Common Deficiencies to Avoid

  • Missing dates/times
  • Illegible entries (if handwritten)
  • Use of prohibited abbreviations
  • Incomplete medication reconciliation
  • Missing informed consent documentation
  • Inadequate follow-up instructions

Cardiology Case Report Considerations

What Makes a Publishable Case

  • Novel presentation of known disease
  • Unexpected treatment response
  • Diagnostic challenge with learning points
  • Rare condition with management insights
  • Adverse event with safety implications

Key Cardiovascular Data to Include

  • ECG findings (with images if relevant)
  • Imaging results (echo, angiography, CT/MRI)
  • Biomarkers (troponin, BNP trends)
  • Hemodynamic data
  • Procedural details and outcomes
  • Long-term follow-up