differential-methylation

This skill performs differential DNA methylation analysis (DMRs and DMCs) between experimental conditions using WGBS methylation tracks (BED/BedGraph). It standardizes input files into per-sample four-column Metilene tables, constructs a merged methylation matrix, runs Metilene for DMR detection, filters the results, and generates quick visualizations.

differential-methylationDNA-methylationWGBSDMR-detection

BIsnake2001

32

integrative-DMR-DEG

This skill performs correlation analysis between differential methylation and differential gene expression, identifying genes with coordinated epigenetic regulation. It provides preprocessing and integration workflows, using promoter-level methylation–expression relationships.

correlation-analysisdifferential-methylationdifferential-expressionepigenetics

BIsnake2001

32