hypogenic
Automated hypothesis generation and testing using large language models. Use this skill when generating scientific hypotheses from datasets, combining literature insights with empirical data, testing hypotheses against observational data, or conducting systematic hypothesis exploration for research discovery in domains like deception detection, AI content detection, mental health analysis, or other empirical research tasks.
histolab
Digital pathology image processing toolkit for whole slide images (WSI). Use this skill when working with histopathology slides, processing H&E or IHC stained tissue images, extracting tiles from gigapixel pathology images, detecting tissue regions, segmenting tissue masks, or preparing datasets for computational pathology deep learning pipelines. Applies to WSI formats (SVS, TIFF, NDPI), tile-based analysis, and histological image preprocessing workflows.
gtars
High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis in computational genomics and machine learning applications.
gget
CLI/Python toolkit for rapid bioinformatics queries. Preferred for quick BLAST searches. Access to 20+ databases: gene info (Ensembl/UniProt), AlphaFold, ARCHS4, Enrichr, OpenTargets, COSMIC, genome downloads. For advanced BLAST/batch processing, use biopython. For multi-database integration, use bioservices.
geniml
This skill should be used when working with genomic interval data (BED files) for machine learning tasks. Use for training region embeddings (Region2Vec, BEDspace), single-cell ATAC-seq analysis (scEmbed), building consensus peaks (universes), or any ML-based analysis of genomic regions. Applies to BED file collections, scATAC-seq data, chromatin accessibility datasets, and region-based genomic feature learning.
flowio
Parse FCS (Flow Cytometry Standard) files v2.0-3.1. Extract events as NumPy arrays, read metadata/channels, convert to CSV/DataFrame, for flow cytometry data preprocessing.
etetoolkit
Phylogenetic tree toolkit (ETE). Tree manipulation (Newick/NHX), evolutionary event detection, orthology/paralogy, NCBI taxonomy, visualization (PDF/SVG), for phylogenomics.
esm
Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inference.
diffdock
Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.
denario
Multiagent AI system for scientific research assistance that automates research workflows from data analysis to publication. This skill should be used when generating research ideas from datasets, developing research methodologies, executing computational experiments, performing literature searches, or generating publication-ready papers in LaTeX format. Supports end-to-end research pipelines with customizable agent orchestration.
code-review
Use when receiving code review feedback (especially if unclear or technically questionable), when completing tasks or major features requiring review before proceeding, or before making any completion/success claims. Covers three practices - receiving feedback with technical rigor over performative agreement, requesting reviews via code-reviewer subagent, and verification gates requiring evidence before any status claims. Essential for subagent-driven development, pull requests, and preventing false completion claims.
cloudflare-zero-trust-access
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cloudflare-workflows
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cloudflare-workers-ai
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cloudflare-worker-base
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cloudflare-vectorize
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cloudflare-turnstile
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cloudflare-sandbox
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cloudflare-r2
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cloudflare-queues
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cloudflare-nextjs
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cloudflare-mcp-server
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cloudflare-kv
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cloudflare-images
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cloudflare-hyperdrive
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cloudflare-full-stack-scaffold
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cloudflare-full-stack-integration
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cloudflare-email-routing
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cloudflare-durable-objects
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cloudflare-d1
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cloudflare-cron-triggers
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cloudflare-browser-rendering
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cloudflare-agents
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clerk-auth
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claude-git-branching
Expert Git workflow management for Claude Code sessions with branch naming conventions, push retry logic, conflict resolution, and PR automation specifically designed for AI-assisted development workflows.
d3-viz
Creating interactive data visualisations using d3.js. This skill should be used when creating custom charts, graphs, network diagrams, geographic visualisations, or any complex SVG-based data visualisation that requires fine-grained control over visual elements, transitions, or interactions. Use this for bespoke visualisations beyond standard charting libraries, whether in React, Vue, Svelte, vanilla JavaScript, or any other environment.
claude-api
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claude-agent-sdk
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chrome-devtools
Browser automation, debugging, and performance analysis using Puppeteer CLI scripts. Use for automating browsers, taking screenshots, analyzing performance, monitoring network traffic, web scraping, form automation, and JavaScript debugging.
checkpoint-workflow-builder
Build resumable state-machine workflows with checkpoint patterns, progress preservation, and automatic recovery for complex multi-phase operations that need to survive interruptions, timeouts, and failures.
browser-app-creator
Creates complete single-file HTML/CSS/JS web apps with localStorage persistence, ADHD-optimized UI (60px+ buttons), dark mode, and offline functionality. Use when user says "create app", "build tool", "make dashboard", or requests any browser-based interface.
brainstorming
Use when creating or developing, before writing code or implementation plans - refines rough ideas into fully-formed designs through collaborative questioning, alternative exploration, and incremental validation. Don't use during clear 'mechanical' processes
哔哩哔哩字幕获取器
从哔哩哔哩(B站)搜索视频、获取字幕并转换为 Markdown 格式。当用户需要搜索 B 站视频、下载视频字幕、批量获取字幕、分析视频内容时使用。支持关键词搜索、单视频处理、批量并发下载。
better-chatbot
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better-chatbot-patterns
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better-auth
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bash-script-helper
Expert helper for bash scripting, debugging, and best practices
base-ui-react
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backend-dev-guidelines
Comprehensive backend development guide for Node.js/Express/TypeScript microservices. Use when creating routes, controllers, services, repositories, middleware, or working with Express APIs, Prisma database access, Sentry error tracking, Zod validation, unifiedConfig, dependency injection, or async patterns. Covers layered architecture (routes → controllers → services → repositories), BaseController pattern, error handling, performance monitoring, testing strategies, and migration from legacy patterns.
auto-animate
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