markitdown
将文件和办公文档转换为 Markdown。支持 PDF、DOCX、PPTX、XLSX、图片（含 OCR）、音频（含转录）、HTML、CSV、JSON、XML、ZIP、YouTube 链接、EPub 等多种格式。
market-research-reports
描述：生成全面的市场研究报告（50 页以上），风格参考顶级咨询公司（如 McKinsey、BCG、Gartner）。具备专业的 LaTeX 排版、大量基于科学示意图和图像生成的可视化内容、与 research-lookup 深度集成以进行数据收集，以及多框架战略分析能力，包括波特五力模型（Porter’s Five Forces）、PESTLE 分析、SWOT 分析、TAM/SAM/SOM 市场规模分析和 BCG 矩阵。
clinical-decision-support
用于制药和临床研究环境中生成专业临床决策支持（CDS）文档，包括患者队列分析（基于生物标志物分层并结合结局分析）以及治疗推荐报告（基于循证指南并包含决策算法）。支持 GRADE 证据分级、统计分析（如风险比、 生存曲线、瀑布图）、生物标志物整合以及监管合规要求。输出为可发表级别的 LaTeX/PDF 格式，针对药物开发、临床研究和证据综合进行了优化。
clinical-reports
用于撰写全面的临床报告，包括病例报告（遵循 CARE 指南）、诊断报告（影像学/病理学/实验室）、临床试验报告（ICH-E3、SAE、CSR）以及患者文书（SOAP 记录、病史与体格检查 H&P、出院小结）。提供完整模板支持、监管合规（HIPAA、FDA、ICH-GCP）以及验证工具。
literature-review
使用多个学术数据库（如 PubMed、arXiv、bioRxiv、Semantic Scholar 等）开展全面、系统化的文献综述。适用于系统综述、Meta 分析、研究综合，或跨生物医学、科学和技术领域的全面文献检索。可生成包含已验证引用的专业格式 Markdown 文档和 PDF，支持多种引用格式（如 APA、Nature、Vancouver 等）。
pptx
演示文稿工具包（.pptx）。可创建/编辑幻灯片、版式、内容、演讲者备注和批注，用于以编程方式创建和修改演示文稿。
generate-image
Generate or edit images using AI models (FLUX, Gemini). Use for general-purpose image generation including photos, illustrations, artwork, visual assets, concept art, and any image that isn't a technical diagram or schematic. For flowcharts, circuits, pathways, and technical diagrams, use the scientific-schematics skill instead.
hypothesis-generation
Generate testable hypotheses. Formulate from observations, design experiments, explore competing explanations, develop predictions, propose mechanisms, for scientific inquiry across domains.
latex-posters
使用 LaTeX（如 beamerposter、tikzposter 或 baposter）创建专业科研海报。支持会议展示、学术海报和科学传播。包含版式设计、配色方案、多栏布局、图形整合，以及面向海报视觉传达的最佳实践。
gget
快速CLI/Python查询20+生物信息学数据库。用于快速查找：基因信息、BLAST搜索、AlphaFold结构、富集分析。最适合交互式探索、简单查询。批处理或高级BLAST请使用biopython；多数据库Python工作流请使用bioservices。
smart-search
基于 opencli 命令的智能搜索路由器。当用户想要搜索、查询、查找或研究信息时，尤其是涉及指定网站、社交媒体、技术资料、新闻、购物、旅游、求职、金融或中文内容时，务必使用此 skill
opencli-usage
Use when running OpenCLI commands to interact with websites (Bilibili, Twitter, Reddit, Xiaohongshu, etc.), desktop apps (Cursor, Notion), or public APIs (HackerNews, arXiv). Covers installation, command reference, and output formats for 79+ adapters.
opencli-repair
Diagnose and fix broken OpenCLI adapters when websites change. Use when an opencli command fails with SELECTOR, EMPTY_RESULT, API_ERROR, or PAGE_CHANGED errors. Reads structured diagnostic output and uses browser automation to discover what changed and patch the adapter.
opencli-operate
Make websites accessible for AI agents. Navigate, click, type, extract, wait — using Chrome with existing login sessions. No LLM API key needed.
opencli-oneshot
Use when quickly generating a single OpenCLI command from a specific URL and goal description. 4-step process — open page, capture API, write YAML adapter, test. For full site exploration, use opencli-explorer instead.
pydeseq2
差异基因表达分析(Python DESeq2)。从bulk RNA-seq计数中识别差异表达基因，Wald检验，FDR校正，火山图/MA图，用于RNA-seq分析。
pysam
基因组文件工具包。读写SAM/BAM/CRAM比对文件、VCF/BCF变异文件、FASTA/FASTQ序列，提取区域，计算覆盖度，用于NGS数据处理管道。
scanpy
标准单细胞RNA-seq分析管道。用于质控、标准化、降维(PCA/UMAP/t-SNE)、聚类、差异表达和可视化。最适合具有成熟工作流的探索性scRNA-seq分析。深度学习模型请使用scvi-tools；数据格式问题请使用anndata。
scikit-bio
生物数据工具包。序列分析、比对、系统发育树、多样性度量(alpha/beta, UniFrac)、排序(PCoA)、PERMANOVA、FASTA/Newick I/O，用于微生物组分析。
opencli-explorer
Use when creating a new OpenCLI adapter from scratch, adding support for a new website or platform, or exploring a site's API endpoints via browser DevTools. Covers API discovery workflow, authentication strategy selection, YAML/TS adapter writing, and testing.
pubmed-database
直接访问PubMed REST API。高级布尔/MeSH查询、E-utilities API、批量处理、引文管理。对于Python工作流，建议使用biopython (Bio.Entrez)。此技能适用于直接HTTP/REST操作或自定义API实现。
用于提取文本与表格、创建新 PDF、合并/拆分文档以及处理表单的综合 PDF 操作工具包。当需要填写 PDF 表单，或以编程方式批量处理、生成或分析 PDF 文档时使用。
uniprot-database
直接访问UniProt REST API。蛋白质搜索、FASTA序列获取、ID映射、Swiss-Prot/TrEMBL数据库。对于涉及多个数据库的Python工作流，建议使用bioservices（统一接口覆盖40多个服务）。此技能适用于直接HTTP/REST操作或UniProt特定控制。
anndata
单细胞分析中带注释矩阵的数据结构。用于处理.h5ad文件或与scverse生态系统集成。这是数据格式技能——用于分析工作流请使用scanpy；用于概率模型请使用scvi-tools；用于群体规模查询请使用cellxgene-census。
biopython
综合分子生物学工具包。用于序列操作、文件解析(FASTA/GenBank/PDB)、系统发育学和程序化NCBI/PubMed访问(Bio.Entrez)。最适合批处理、定制生物信息学管道、BLAST自动化。快速查找请使用gget；多服务集成请使用bioservices。
cloudflare-agents-sdk
Build AI agents on Cloudflare Workers using the Agents SDK. Load when creating stateful agents, durable workflows, real-time WebSocket apps, scheduled tasks, MCP servers, or chat applications. Covers Agent class, state management, callable RPC, Workflows integration, and React hooks.
cloudflare-ai-agent
Build AI agents on Cloudflare using the Agents SDK with state management, real-time WebSockets, scheduled tasks, tool integration, and chat capabilities. Generates production-ready agent code deployed to Workers.
cloudflare-durable-objects
Create and review Cloudflare Durable Objects. Use when building stateful coordination (chat rooms, multiplayer games, booking systems), implementing RPC methods, SQLite storage, alarms, WebSockets, or reviewing DO code for best practices.
cloudflare-mcp-server
Build remote MCP (Model Context Protocol) servers on Cloudflare Workers with tools, OAuth authentication, and production deployment. Use when building MCP servers, creating MCP tools, remote MCP, deploying MCP, or adding OAuth to MCP.
cloudflare-sandbox-sdk
Build sandboxed applications for secure code execution on Cloudflare. Use when building AI code execution, code interpreters, CI/CD systems, interactive dev environments, or executing untrusted code.
cloudflare-web-perf
Analyzes web performance using Chrome DevTools MCP. Measures Core Web Vitals (LCP, INP, CLS) and supplementary metrics, identifies render-blocking resources, network chains, layout shifts, caching issues, and accessibility gaps. Use when asked to audit, profile, debug, or optimize page load performance.
cloudflare-workers-best-practices
Reviews and authors Cloudflare Workers code against production best practices. Use when writing new Workers, reviewing Worker code, configuring wrangler.jsonc, or checking for common Workers anti-patterns.
cloudflare-wrangler
Cloudflare Workers CLI for deploying, developing, and managing Workers, KV, R2, D1, Vectorize, Hyperdrive, Workers AI, Containers, Queues, Workflows, Pipelines, and Secrets Store. Use before running wrangler commands to ensure correct syntax and best practices.
cloudflare
Comprehensive Cloudflare platform skill covering Workers, Pages, storage (KV, D1, R2), AI (Workers AI, Vectorize, Agents SDK), networking (Tunnel, Spectrum), security (WAF, DDoS), and infrastructure-as-code (Terraform, Pulumi). Use for any Cloudflare development task.
context7
Retrieve up-to-date documentation and code examples from Context7. Use when you need library/framework documentation or API examples.
convex-auth-setup
Set up Convex authentication with proper user management, identity mapping, and access control patterns. Use when implementing auth flows.
convex-components-guide
Guide to using Convex components for feature encapsulation. Learn about sibling components, creating your own, and when to use components vs monolithic code.
use-railway
Operate Railway infrastructure. Create projects, provision services and databases, manage object storage buckets, deploy code, configure environments and variables, manage domains, troubleshoot failures, check status and metrics, and query Railway docs. Use this skill whenever the user mentions Railway, deployments, services, environments, buckets, object storage, build failures, or infrastructure operations.
models-dev
Look up current LLM model information, capabilities, pricing, context windows, and comparisons using models.dev data. Use when asked about AI models, model capabilities, pricing, or provider comparisons.
kernel
Remote browser automation using the Kernel CLI. Use when the agent needs to interact with cloud browsers for web automation, scraping, screenshots, or running browser-based tasks.
github
GitHub workflow best practices using gh CLI and git. Use when working with GitHub repositories, pull requests, issues, or GitHub interactions.
frontend-design
Create distinctive, production-grade frontend interfaces with high design quality. Use this skill when the user asks to build web components, pages, artifacts, posters, or applications (examples include websites, landing pages, dashboards, React components, HTML/CSS layouts, or when styling/beautifying any web UI). Generates creative, polished code and UI design that avoids generic AI aesthetics.
doppler
Manage project secrets using the Doppler CLI. Use when setting up, accessing, injecting, or managing environment secrets, service tokens, CI/CD integration, or secret rotation for any language or platform.
convex
Umbrella skill for all Convex development patterns. Routes to specific skills for quickstart, functions, schema, auth, migrations, components, and helpers.
convex-schema-builder
Design and generate Convex database schemas with proper validation, indexes, and relationships. Use when creating schema.ts or modifying table definitions.
convex-quickstart
Initialize a new Convex backend from scratch with schema, auth, and basic CRUD operations. Use when starting a new project or adding Convex to an existing app.
convex-migration-helper
Plan and execute Convex schema migrations safely, including adding fields, creating tables, and data transformations. Use when schema changes affect existing data.
convex-helpers-guide
Discover and use convex-helpers utilities for relationships, filtering, sessions, custom functions, and more. Use when you need pre-built Convex patterns.
convex-function-creator
Create Convex queries, mutations, and actions with proper validation, authentication, and error handling. Use when implementing new API endpoints.
browser-test
Execute browser-based UI testing using Chrome MCP tools. Tests user interactions, visual outcomes, captures evidence. Use for UI features after implementation and security review.
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