biorxiv-database
Efficient database search tool for bioRxiv preprint server. Use this skill when searching for life sciences preprints by keywords, authors, date ranges, or categories, retrieving paper metadata, downloading PDFs, or conducting literature reviews.
biopython
Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use bioservices.
benchling-integration
Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.
astropy
Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmological distance calculations, time scale conversions, or astronomical data processing.
arboreto
Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
anndata
Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.
alphafold-database
Access AlphaFold 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.
aeon
This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
adaptyv
Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
webapp-testing
Toolkit for interacting with and testing local web applications using Playwright. Supports verifying frontend functionality, debugging UI behavior, capturing browser screenshots, and viewing browser logs.
web-artifacts-builder
Suite of tools for creating elaborate, multi-component claude.ai HTML artifacts using modern frontend web technologies (React, Tailwind CSS, shadcn/ui). Use for complex artifacts requiring state management, routing, or shadcn/ui components - not for simple single-file HTML/JSX artifacts.
theme-factory
Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc. There are 10 pre-set themes with colors/fonts that you can apply to any artifact that has been creating, or can generate a new theme on-the-fly.
slack-gif-creator
Knowledge and utilities for creating animated GIFs optimized for Slack. Provides constraints, validation tools, and animation concepts. Use when users request animated GIFs for Slack like "make me a GIF of X doing Y for Slack."
skill-creator
Guide for creating effective skills. This skill should be used when users want to create a new skill (or update an existing skill) that extends Claude's capabilities with specialized knowledge, workflows, or tool integrations.
mcp-builder
Guide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with external services through well-designed tools. Use when building MCP servers to integrate external APIs or services, whether in Python (FastMCP) or Node/TypeScript (MCP SDK).
internal-comms
A set of resources to help me write all kinds of internal communications, using the formats that my company likes to use. Claude should use this skill whenever asked to write some sort of internal communications (status reports, leadership updates, 3P updates, company newsletters, FAQs, incident reports, project updates, etc.).
frontend-design
Create distinctive, production-grade frontend interfaces with high design quality. Use this skill when the user asks to build web components, pages, artifacts, posters, or applications (examples include websites, landing pages, dashboards, React components, HTML/CSS layouts, or when styling/beautifying any web UI). Generates creative, polished code and UI design that avoids generic AI aesthetics.
doc-coauthoring
Guide users through a structured workflow for co-authoring documentation. Use when user wants to write documentation, proposals, technical specs, decision docs, or similar structured content. This workflow helps users efficiently transfer context, refine content through iteration, and verify the doc works for readers. Trigger when user mentions writing docs, creating proposals, drafting specs, or similar documentation tasks.
canvas-design
Create beautiful visual art in .png and .pdf documents using design philosophy. You should use this skill when the user asks to create a poster, piece of art, design, or other static piece. Create original visual designs, never copying existing artists' work to avoid copyright violations.
brand-guidelines
Applies Anthropic's official brand colors and typography to any sort of artifact that may benefit from having Anthropic's look-and-feel. Use it when brand colors or style guidelines, visual formatting, or company design standards apply.
algorithmic-art
Creating algorithmic art using p5.js with seeded randomness and interactive parameter exploration. Use this when users request creating art using code, generative art, algorithmic art, flow fields, or particle systems. Create original algorithmic art rather than copying existing artists' work to avoid copyright violations.
tdd-workflow
Use this skill when writing new features, fixing bugs, or refactoring code. Enforces test-driven development with 80%+ coverage including unit, integration, and E2E tests.
strategic-compact
Suggests manual context compaction at logical intervals to preserve context through task phases rather than arbitrary auto-compaction.
springboot-tdd
Test-driven development for Spring Boot using JUnit 5, Mockito, MockMvc, Testcontainers, and JaCoCo. Use when adding features, fixing bugs, or refactoring.
springboot-security
Spring Security best practices for authn/authz, validation, CSRF, secrets, headers, rate limiting, and dependency security in Java Spring Boot services.
springboot-patterns
Spring Boot architecture patterns, REST API design, layered services, data access, caching, async processing, and logging. Use for Java Spring Boot backend work.
security-review
Use this skill when adding authentication, handling user input, working with secrets, creating API endpoints, or implementing payment/sensitive features. Provides comprehensive security checklist and patterns.
postgres-patterns
PostgreSQL database patterns for query optimization, schema design, indexing, and security. Based on Supabase best practices.
jpa-patterns
JPA/Hibernate patterns for entity design, relationships, query optimization, transactions, auditing, indexing, pagination, and pooling in Spring Boot.
iterative-retrieval
Pattern for progressively refining context retrieval to solve the subagent context problem
golang-testing
Go testing patterns including table-driven tests, subtests, benchmarks, fuzzing, and test coverage. Follows TDD methodology with idiomatic Go practices.
golang-patterns
Idiomatic Go patterns, best practices, and conventions for building robust, efficient, and maintainable Go applications.
frontend-patterns
Frontend development patterns for React, Next.js, state management, performance optimization, and UI best practices.
eval-harness
Formal evaluation framework for Claude Code sessions implementing eval-driven development (EDD) principles
continuous-learning
Automatically extract reusable patterns from Claude Code sessions and save them as learned skills for future use.
continuous-learning-v2
Instinct-based learning system that observes sessions via hooks, creates atomic instincts with confidence scoring, and evolves them into skills/commands/agents.
coding-standards
Universal coding standards, best practices, and patterns for TypeScript, JavaScript, React, and Node.js development.
clickhouse-io
ClickHouse database patterns, query optimization, analytics, and data engineering best practices for high-performance analytical workloads.
backend-patterns
Backend architecture patterns, API design, database optimization, and server-side best practices for Node.js, Express, and Next.js API routes.
backend-architect
Expert senior en architecture backend pour accompagner le développement (conception, implémentation, review, refactoring). Architecture hexagonale, DDD, SOLID, clean code, tests. Utiliser pour concevoir de nouvelles features, développer du code, reviewer, refactorer, ou résoudre des problèmes architecturaux.
security-guardian
Expert en sécurité applicative pour détecter les vulnérabilités, auditer le code, et guider les bonnes pratiques de sécurité. OWASP Top 10, authentification, autorisation, cryptographie, gestion de secrets. Utiliser pour audits sécurité, reviews de code sensible, conception de features sécurisées, ou résolution de failles.
oracle
Use the @steipete/oracle CLI to bundle a prompt plus the right files and get a second-model review (API or browser) for debugging, refactors, design checks, or cross-validation.
sheets-cli
Read, write, and update Google Sheets data via CLI. Use when the user asks to read spreadsheet data, update cells, append rows, or work with Google Sheets. Triggers on mentions of spreadsheets, sheets, Google Sheets, tabular data in the cloud, or specific sheet names like "Projects" or "Tasks".
convex
Convex backend development patterns, validators, indexes, actions, queries, mutations, file storage, scheduling, React hooks, and components. Use when writing Convex code, debugging Convex issues, or planning Convex architecture.
github-repo-skill
Guide for creating new GitHub repos and best practice for existing GitHub repos, applicable to both code and non-code projects
thx-boris
Meta-workflow for using Claude Code effectively, based on patterns from Boris Cherny (Claude Code creator). Use when setting up a new project with Claude Code, optimizing an existing workflow, creating CLAUDE.md files, designing subagents, configuring hooks, or running parallel Claude sessions. Triggers on "how should I structure my CLAUDE.md", "create a subagent for X", "set up hooks", "optimize my Claude Code setup".
prompt-engineering
Expert prompt optimization system for building production-ready AI features. Use when users request help improving prompts, want to create system prompts, need prompt review/critique, ask for prompt optimization strategies, want to analyze prompt effectiveness, mention prompt engineering best practices, request prompt templates, or need guidance on structuring AI instructions. Also use when users provide prompts and want suggestions for improvement.
agent-workflow
Expert system for designing and architecting AI agent workflows based on proven Meta methodologies. Use when users need to build AI agents, create agent workflows, solve problems using agentic systems, integrate multiple tools into agent architectures, or need guidance on agent design patterns. Helps translate business problems into structured agent solutions with clear scope, tool integration, and multi-layer architecture planning.
prd-writer
Full 5-stage PRD framework for complex features. Use for deep PRD work via /spec --deep full-prd. For quick feature specs, use /spec --feature instead.
context-engineering
[ARCHIVED] Full 4D Context Canvas reference. For new AI features, use /spec --ai. For debugging, use /ai-debug. For quality checks, use /context-check.
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