opentargets-database
Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.
metabolomics-workbench-database
Access NIH Metabolomics Workbench via REST API (4,200+ studies). Query metabolites, RefMet nomenclature, MS/NMR data, m/z searches, study metadata, for metabolomics and biomarker discovery.
kegg-database
Direct REST API access to KEGG (academic use only). Pathway analysis, gene-pathway mapping, metabolic pathways, drug interactions, ID conversion. For Python workflows with multiple databases, prefer bioservices. Use this for direct HTTP/REST work or KEGG-specific control.
hmdb-database
Access Human Metabolome Database (220K+ metabolites). Search by name/ID/structure, retrieve chemical properties, biomarker data, NMR/MS spectra, pathways, for metabolomics and identification.
gwas-database
Query NHGRI-EBI GWAS Catalog for SNP-trait associations. Search variants by rs ID, disease/trait, gene, retrieve p-values and summary statistics, for genetic epidemiology and polygenic risk scores.
geo-database
Access NCBI GEO for gene expression/genomics data. Search/download microarray and RNA-seq datasets (GSE, GSM, GPL), retrieve SOFT/Matrix files, for transcriptomics and expression analysis.
gene-database
Query NCBI Gene via E-utilities/Datasets API. Search by symbol/ID, retrieve gene info (RefSeqs, GO, locations, phenotypes), batch lookups, for gene annotation and functional analysis.
fda-database
Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.
ensembl-database
Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.
ena-database
Access European Nucleotide Archive via API/FTP. Retrieve DNA/RNA sequences, raw reads (FASTQ), genome assemblies by accession, for genomics and bioinformatics pipelines. Supports multiple formats.
drugbank-database
Access and analyze comprehensive drug information from the DrugBank database including drug properties, interactions, targets, pathways, chemical structures, and pharmacology data. This skill should be used when working with pharmaceutical data, drug discovery research, pharmacology studies, drug-drug interaction analysis, target identification, chemical similarity searches, ADMET predictions, or any task requiring detailed drug and drug target information from DrugBank.
repository-analyzer
Analyzes codebases to generate comprehensive documentation including structure, languages, frameworks, dependencies, design patterns, and technical debt. Use when user says "analyze repository", "understand codebase", "document project", or when exploring unfamiliar code.
repomix
Package entire code repositories into single AI-friendly files using Repomix. Capabilities include pack codebases with customizable include/exclude patterns, generate multiple output formats (XML, Markdown, plain text), preserve file structure and context, optimize for AI consumption with token counting, filter by file types and directories, add custom headers and summaries. Use when packaging codebases for AI analysis, creating repository snapshots for LLM context, analyzing third-party libraries, preparing for security audits, generating documentation context, or evaluating unfamiliar codebases.
react-hook-form-zod
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rapid-prototyper
Creates minimal working prototypes for quick idea validation. Single-file when possible, includes test data, ready to demo immediately. Use when user says "prototype", "MVP", "proof of concept", "quick demo".
pict-test-designer
Design comprehensive test cases using PICT (Pairwise Independent Combinatorial Testing) for any piece of requirements or code. Analyzes inputs, generates PICT models with parameters, values, and constraints for valid scenarios using pairwise testing. Outputs the PICT model, markdown table of test cases, and expected results.
project-session-management
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project-planning
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Playwright Browser Automation
Complete browser automation with Playwright. Auto-detects dev servers, writes clean test scripts to /tmp. Test pages, fill forms, take screenshots, check responsive design, validate UX, test login flows, check links, automate any browser task. Use when user wants to test websites, automate browser interactions, validate web functionality, or perform any browser-based testing.
Browser Daemon
Persistent browser automation via Playwright daemon. Keep a browser window open and send it commands (navigate, execute JS, inspect console). Perfect for interactive debugging, development, and testing web applications. Use when you need to interact with a browser repeatedly without opening/closing it.
openai-responses
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openai-assistants
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openai-api
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openai-agents
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open-source-contributions
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nextjs
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network-diagnostics
Automated network troubleshooting and diagnostics for WSL/Linux environments
neon-vercel-postgres
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frontend-dev-guidelines
Frontend development guidelines for React/TypeScript applications. Modern patterns including Suspense, lazy loading, useSuspenseQuery, file organization with features directory, MUI v7 styling, TanStack Router, performance optimization, and TypeScript best practices. Use when creating components, pages, features, fetching data, styling, routing, or working with frontend code.
Fluxwing Screenshot Importer
Import UI screenshots and generate uxscii components automatically using vision analysis. Use when user wants to import, convert, or generate .uxm components from screenshots or images.
Fluxwing Library Browser
Browse and view all available uxscii components including bundled templates, user components, and screens. Use when working with .uxm files, when user wants to see, list, browse, or search .uxm components or screens.
fastmcp
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executing-plans
Use when partner provides a complete implementation plan to execute in controlled batches with review checkpoints - loads plan, reviews critically, executes tasks in batches, reports for review between batches
error-tracking
Add Sentry v8 error tracking and performance monitoring to your project services. Use this skill when adding error handling, creating new controllers, instrumenting cron jobs, or tracking database performance. ALL ERRORS MUST BE CAPTURED TO SENTRY - no exceptions.
dispatching-parallel-agents
Use when facing 3+ independent failures that can be investigated without shared state or dependencies - dispatches multiple Claude agents to investigate and fix independent problems concurrently
devops
Deploy and manage cloud infrastructure on Cloudflare (Workers, R2, D1, KV, Pages, Durable Objects, Browser Rendering), Docker containers, and Google Cloud Platform (Compute Engine, GKE, Cloud Run, App Engine, Cloud Storage). Use when deploying serverless functions to the edge, configuring edge computing solutions, managing Docker containers and images, setting up CI/CD pipelines, optimizing cloud infrastructure costs, implementing global caching strategies, working with cloud databases, or building cloud-native applications.
defense-in-depth
Use when invalid data causes failures deep in execution, requiring validation at multiple system layers - validates at every layer data passes through to make bugs structurally impossible
code-review
Use when receiving code review feedback (especially if unclear or technically questionable), when completing tasks or major features requiring review before proceeding, or before making any completion/success claims. Covers three practices - receiving feedback with technical rigor over performative agreement, requesting reviews via code-reviewer subagent, and verification gates requiring evidence before any status claims. Essential for subagent-driven development, pull requests, and preventing false completion claims.
cloudflare-zero-trust-access
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cloudflare-r2
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cloudflare-kv
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cloudflare-images
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cloudflare-hyperdrive
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cloudflare-durable-objects
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cloudflare-d1
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cloudflare-cron-triggers
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cloudflare-browser-rendering
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chrome-devtools
Browser automation, debugging, and performance analysis using Puppeteer CLI scripts. Use for automating browsers, taking screenshots, analyzing performance, monitoring network traffic, web scraping, form automation, and JavaScript debugging.
checkpoint-workflow-builder
Build resumable state-machine workflows with checkpoint patterns, progress preservation, and automatic recovery for complex multi-phase operations that need to survive interruptions, timeouts, and failures.
browser-app-creator
Creates complete single-file HTML/CSS/JS web apps with localStorage persistence, ADHD-optimized UI (60px+ buttons), dark mode, and offline functionality. Use when user says "create app", "build tool", "make dashboard", or requests any browser-based interface.
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