chembl-database
Query ChEMBL's bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.
clinicaltrials-database
Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.
clinpgx-database
Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.
base-ui-react
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backend-dev-guidelines
Comprehensive backend development guide for Node.js/Express/TypeScript microservices. Use when creating routes, controllers, services, repositories, middleware, or working with Express APIs, Prisma database access, Sentry error tracking, Zod validation, unifiedConfig, dependency injection, or async patterns. Covers layered architecture (routes → controllers → services → repositories), BaseController pattern, error handling, performance monitoring, testing strategies, and migration from legacy patterns.
browser-app-creator
Creates complete single-file HTML/CSS/JS web apps with localStorage persistence, ADHD-optimized UI (60px+ buttons), dark mode, and offline functionality. Use when user says "create app", "build tool", "make dashboard", or requests any browser-based interface.
clinvar-database
Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.
cosmic-database
Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.
cloudflare-turnstile
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astropy
Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmological distance calculations, time scale conversions, or astronomical data processing.
cloudflare-vectorize
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cloudflare-worker-base
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cloudflare-workers-ai
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auto-animate
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auth-js
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api-integration-builder
Generates production-ready API clients with TypeScript types, retry logic, rate limiting, authentication (OAuth, API keys), error handling, and mock responses. Use when user says "integrate API", "API client", "connect to service", or requests third-party service integration.
cloudflare-workflows
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ai-sdk-ui
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ai-sdk-core
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cloudflare-zero-trust-access
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ai-multimodal
Process and generate multimedia content using Google Gemini API. Capabilities include analyze audio files (transcription with timestamps, summarization, speech understanding, music/sound analysis up to 9.5 hours), understand images (captioning, object detection, OCR, visual Q&A, segmentation), process videos (scene detection, Q&A, temporal analysis, YouTube URLs, up to 6 hours), extract from documents (PDF tables, forms, charts, diagrams, multi-page), generate images (text-to-image, editing, composition, refinement). Use when working with audio/video files, analyzing images or screenshots, processing PDF documents, extracting structured data from media, creating images from text prompts, or implementing multimodal AI features. Supports multiple models (Gemini 2.5/2.0) with context windows up to 2M tokens.
code-review
Use when receiving code review feedback (especially if unclear or technically questionable), when completing tasks or major features requiring review before proceeding, or before making any completion/success claims. Covers three practices - receiving feedback with technical rigor over performative agreement, requesting reviews via code-reviewer subagent, and verification gates requiring evidence before any status claims. Essential for subagent-driven development, pull requests, and preventing false completion claims.
typescript-mcp
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ui-styling
Create beautiful, accessible user interfaces with shadcn/ui components (built on Radix UI + Tailwind), Tailwind CSS utility-first styling, and canvas-based visual designs. Use when building user interfaces, implementing design systems, creating responsive layouts, adding accessible components (dialogs, dropdowns, forms, tables), customizing themes and colors, implementing dark mode, generating visual designs and posters, or establishing consistent styling patterns across applications.
tinacms
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ai-elements-chatbot
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claude-code-bash-patterns
|
web-frameworks
Build modern full-stack web applications with Next.js (App Router, Server Components, RSC, PPR, SSR, SSG, ISR), Turborepo (monorepo management, task pipelines, remote caching, parallel execution), and RemixIcon (3100+ SVG icons in outlined/filled styles). Use when creating React applications, implementing server-side rendering, setting up monorepos with multiple packages, optimizing build performance and caching strategies, adding icon libraries, managing shared dependencies, or working with TypeScript full-stack projects.
web-asset-generator
Generate web assets including favicons, app icons (PWA), and social media meta images (Open Graph) for Facebook, Twitter, WhatsApp, and LinkedIn. Use when users need icons, favicons, social sharing images, or Open Graph images from logos or text slogans. Handles image resizing, text-to-image generation, and provides proper HTML meta tags.
verification-before-completion
Use when about to claim work is complete, fixed, or passing, before committing or creating PRs - requires running verification commands and confirming output before making any success claims; evidence before assertions always
pydicom
Python library for working with DICOM (Digital Imaging and Communications in Medicine) files. Use this skill when reading, writing, or modifying medical imaging data in DICOM format, extracting pixel data from medical images (CT, MRI, X-ray, ultrasound), anonymizing DICOM files, working with DICOM metadata and tags, converting DICOM images to other formats, handling compressed DICOM data, or processing medical imaging datasets. Applies to tasks involving medical image analysis, PACS systems, radiology workflows, and healthcare imaging applications.
pict-test-designer
Design comprehensive test cases using PICT (Pairwise Independent Combinatorial Testing) for any piece of requirements or code. Analyzes inputs, generates PICT models with parameters, values, and constraints for valid scenarios using pairwise testing. Outputs the PICT model, markdown table of test cases, and expected results.
rapid-prototyper
Creates minimal working prototypes for quick idea validation. Single-file when possible, includes test data, ready to demo immediately. Use when user says "prototype", "MVP", "proof of concept", "quick demo".
react-hook-form-zod
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sharing-skills
Use when you've developed a broadly useful skill and want to contribute it upstream via pull request - guides process of branching, committing, pushing, and creating PR to contribute skills back to upstream repository
repomix
Package entire code repositories into single AI-friendly files using Repomix. Capabilities include pack codebases with customizable include/exclude patterns, generate multiple output formats (XML, Markdown, plain text), preserve file structure and context, optimize for AI consumption with token counting, filter by file types and directories, add custom headers and summaries. Use when packaging codebases for AI analysis, creating repository snapshots for LLM context, analyzing third-party libraries, preparing for security audits, generating documentation context, or evaluating unfamiliar codebases.
repository-analyzer
Analyzes codebases to generate comprehensive documentation including structure, languages, frameworks, dependencies, design patterns, and technical debt. Use when user says "analyze repository", "understand codebase", "document project", or when exploring unfamiliar code.
deeptools
NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.
session-timeout-handler
Build timeout-resistant Claude Code workflows with chunking strategies, checkpoint patterns, progress tracking, and resume mechanisms to handle 2-minute tool timeouts and ensure reliable completion of long-running operations.
session-launcher
Restores full context when user says "hi-ai" or starts a new conversation. Searches project files, loads memory indexes, reads session state, and creates visual dashboard showing current project, recent decisions, active blockers, and quick actions. Use when user says "hi-ai", "continue", "restore context", or starts a fresh conversation.
sequential-thinking
Use when complex problems require systematic step-by-step reasoning with ability to revise thoughts, branch into alternative approaches, or dynamically adjust scope. Ideal for multi-stage analysis, design planning, problem decomposition, or tasks with initially unclear scope.
denario
Multiagent AI system for scientific research assistance that automates research workflows from data analysis to publication. This skill should be used when generating research ideas from datasets, developing research methodologies, executing computational experiments, performing literature searches, or generating publication-ready papers in LaTeX format. Supports end-to-end research pipelines with customizable agent orchestration.
diffdock
Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.
esm
Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inference.
etetoolkit
Phylogenetic tree toolkit (ETE). Tree manipulation (Newick/NHX), evolutionary event detection, orthology/paralogy, NCBI taxonomy, visualization (PDF/SVG), for phylogenomics.
statistical-analysis
Statistical analysis toolkit. Hypothesis tests (t-test, ANOVA, chi-square), regression, correlation, Bayesian stats, power analysis, assumption checks, APA reporting, for academic research.
scientific-writing
Write scientific manuscripts. IMRAD structure, citations (APA/AMA/Vancouver), figures/tables, reporting guidelines (CONSORT/STROBE/PRISMA), abstracts, for research papers and journal submissions.
scientific-visualization
Create publication figures with matplotlib/seaborn/plotly. Multi-panel layouts, error bars, significance markers, colorblind-safe, export PDF/EPS/TIFF, for journal-ready scientific plots.
scientific-critical-thinking
Evaluate research rigor. Assess methodology, experimental design, statistical validity, biases, confounding, evidence quality (GRADE, Cochrane ROB), for critical analysis of scientific claims.
pydeseq2
Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.
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